![]() “Our adrenal glands have pretty much everything you’d see in that of a fetus during early development,” says Sasaki. What’s more, the lab-grown glands produced the stress-linked hormone cortisol, as well as pregnenolone, a molecule that the body uses to make many hormones, including testosterone, oestrogen and progesterone. The pattern of gene activity was also similar between lab-grown glands and the fetal ones. The lab-grown glands contained all the major cell types and features found in the glands of a fetus in the second trimester of pregnancy. Now, Kotaro Sasaki at the University of Pennsylvania and his colleagues have grown IPS cells derived from the blood of three people into adrenal glands that are roughly 2 millimetres wide. ![]() What lab-grown 'mini-brains' are revealing about this mysterious organ ![]()
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